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HPLC of Abbott-53385 in dog rat and human plasma
Summary
Type:
HPLC
Application #:
104950
Catalog#:
720120.46 - MN HPLC Column, Nucleosil C18, 100A, 5um, 4.6x150mm
Detection:
UV, 240nm
Conditions:
eluent: methanol - acetonitrile - 85% phosphoric acid - water (40:18:0.2:41.8, v/v)
flow rate 1.0ml/min
Authors:
Thomas EW
Source:
J Liquid Chromatogr 9 (1986) 1479 - 1487
Details
Legend: Fig. 2. Chromatograms of A) extracted blank dog plasma, B) extracted dog plasma spiked with 0.5 µg/ml I (1) and internal standard (2), C) processed dog plasma, 0.5h post dosing of 0.3mg/kg I.
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